PolysacDB Core oligosaccharide 2301
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Core oligosaccharide
[edit] Carbohydrate Class
Core oligosaccharide [LPS]
[edit] Source Microbe
Campylobacter fetus
[edit] Basic Structure
The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen)
[edit] Proposed functions
The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab M1823
[edit] Antibody type and class
N/A
[edit] Assay System
ELISA and immunoblotting
[edit] Cross-reactivity
This Mab was highly specific tp C. fetus strains and reacted with serotype A and B strains
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
Due to its high specificity, this Mab is potentially useful as immunodiagnostic reagent for detection, identification and characterization of C. fetus
