PolysacDB Capsular polysaccharide 1853

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Neisseria meningitidis group C strain C11

[edit] Basic Structure

It consists of a homopolymer of α(2-->9)-linked sialic acid residues

[edit] Proposed functions

It is an important virulence factor

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 1846.13

[edit] Antibody type and class

IgG3

[edit] Assay System

Fluorescence ELISA, Ouchterlony precipitation, Bacterial agglutination assay, Bactericidal assay

[edit] Cross-reactivity

This Mab was highly specific to group C polysaccharide and did not react with K1 polysaccharide

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab had bactericidal activity

[edit] Weblink

PubMed

[edit] External Links

• Link to PolysacDB database