PolysacDB Capsular polysaccharide 1070

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Group B type 15 meningococci

[edit] Basic Structure

The capsular polysaccharide, also known as K-antigen consists of repeating units of following residues : -8)α-Neup5Ac(2- [a homopolymer of α(2-->8) sialic acid residues]

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

live group B type 15 meningococci cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 2-2-B

[edit] Antibody type and class

IgM

[edit] Assay System

ELISA and Radioimmunoassay

[edit] Cross-reactivity

This antibody cross-reacted with E. coli strain K1 Capsular polysaccharide

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab provided protection against the E. coli K-1 strain

[edit] Weblink

[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC261141 &tool=pmcentrez&rendertype=abstract PubMed Central]

[edit] External Links

• BCSDB Structural Detail

• Link to PolysacDB database