Parathyroid hormone receptor precursor

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Source Organism 2 Taxomomy 3 Subcellular Localization 4 Developmental Stage 5 Similarity 6 Post translational Modification 7 Function

[edit] Source Organism

Homo sapiens (Human).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.

[edit] Subcellular Localization

Membrane; multi-pass membrane protein.

[edit] Developmental Stage

[edit] Similarity

Belongs to the G-protein coupled receptor 2 family.

[edit] Post translational Modification

[edit] Function

This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTHR2 may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTHR2 presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity).