Corticotropin-releasing factor receptor 2 precursor

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Source Organism 2 Taxomomy 3 Subcellular Localization 4 Developmental Stage 5 Similarity 6 Post translational Modification 7 Function

[edit] Source Organism

Xenopus laevis (African clawed frog).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.

[edit] Subcellular Localization

Membrane; multi-pass membrane protein.

[edit] Developmental Stage

[edit] Similarity

Belongs to the G-protein coupled receptor 2 family.

[edit] Post translational Modification

[edit] Function

This is a receptor for corticotropin releasing factor. Shows high-affinity binding for urotensin I. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).