Colchicine analog

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Colchicine analog
Systematic (IUPAC) name
3,4,5-trimethoxy-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]benzamide
Identifiers
CAS number	?
ATC code	?
PubChem	84075
ChemSpider	75852
Chemical data
Formula	C30H33NO9
Mol. mass	551.58432
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Contents 1 Description 2 General Properties 3 Toxicity 4 External Links

[edit] Description

[edit] General Properties

*Molecular Weight

551.58432

*Molecular Formula

C₃₀H₃₃NO₉

*IUPAC NAME

3,4,5-trimethoxy-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]benzamide

*Canonical Smiles

COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)C4=CC(=C(C(=C4)OC)OC)OC

*Isomeric Smiles

COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)C4=CC(=C(C(=C4)OC)OC)OC

*XLogP

2.6

*Topological Polar Surface Area

111

[edit] Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source

mouse LDLo intramuscular 99288ug/kg (99.288mg/kg) Journal of Medicinal Chemistry. Vol. 26, Pg. 1365, 1983.

[edit] External Links

• Pubchem

Link to BIAdb Database