CarboDB Smooth Lipopolysaccharide 1168
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Smooth Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Bordetella parapertusis
[edit] Basic Structure
The O-chain of these bacteria was reported as a homopolymer of 1,4-linked 2,3-diacetamido-2,3- dideoxy-α-galacturonic acid. This polymer contains several amidated uronic acids, the number of which varies between strains
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
B. parapertusis whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab PP8
[edit] Antibody type and class
IgG3
[edit] Assay System
ELISA and ELISA Inhibition assay
[edit] Cross-reactivity
This Mab did not react with the B. pertussis LPS but cross-reacted with B. bronchiseptica LPS
[edit] Proposed epitopes
The epitope was found to reside on O-chains in addition to sugar units in the core
[edit] Proposed Utility
This Mab was used for structurural elucidation of the epitope
