Capaurine

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Capaurine
Systematic (IUPAC) name
(13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol
Identifiers
CAS number	?
ATC code	?
PubChem	94149
ChemSpider	84966
Chemical data
Formula	C21H25NO5
Mol. mass	371.4269
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Contents 1 Description 2 General Properties 3 Source 4 Function 5 Toxicity 6 External Links 7 Reference

Description

from root tubers of Stephania kwangsiensis H.S. Lo; RN given refers to (S)-isomer

General Properties

*Molecular Weight

371.4269

*Molecular Formula

C₂₁H₂₅NO₅

*IUPAC NAME

(13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol

*Canonical Smiles

COC1=C(C2=C(CC3C4=C(C(=C(C=C4CCN3C2)OC)OC)O)C=C1)OC

*Isomeric Smiles

COC1=C(C2=C(C[C@H]3C4=C(C(=C(C=C4CCN3C2)OC)OC)O)C=C1)OC

*XLogP

2

*Topological Polar Surface Area

60.4

Source

Anomianthus dulcis

Corydalis aurea

Corydalis micrantha

Corydalis montana

Corydalis pallida

Stephania lincangensis

Function

uterine stimulant activity

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source

mouse LD50 intravenous 56mg/kg (56mg/kg) Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 5, Pg. 163, 1946.

External Links

• Pubchem

Link to BIAdb Database

Reference

Harborne,Phytochemical Dictionary Second Edition,Taylor and Francis,(1999),Chapter21