Protoberberine

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Protoberberine
Systematic (IUPAC) name
5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
Identifiers
CAS number	?
ATC code	?
PubChem	114943
Chemical data
Formula	C17H14N+
Mol. mass	232.29976
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Description

a benzyltetrahydroisoquinoline derivative that appears as an isoquinoline annelated (adjoined) with a naphthylene; the nitrogen is typically quarternary; nitidine is annelated differently; RN given refers to parent cpd

The protoberberine alkaloids display a broad diversity of biological activities1,2 and feature predominently as active components in many folkloric medicines especially in China and other Asian countries.

General Properties

*Molecular Weight

232.29976

*Molecular Formula

C₁₇H₁₄N+

*IUPAC NAME

5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium

*Canonical Smiles

C1C[N+]2=CC3=CC=CC=C3C=C2C4=CC=CC=C41

*Isomeric Smiles

N/A

*XLogP

N/A

*Topological Polar Surface Area

3.9

External Links

• Pubchem

Link to BIAdb Database