Fluocinolone Acetonide

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

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A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)

General Properties

*Molecular Weight

452.49

*Molecular Formula

C₂₄H₃₀F₂O₆

*IUPAC NAME

*Canonical Smiles

CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)F)C

*Isomeric Smiles

CC1(O[C@@H]2C[C@H]3[C@@H]4C[C@@H](C5=CC(=O)C=C[C@@]5([C@]4([C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)F)C)F)C

PhysioChemical Properties

*Melting Point

265-266(EXP)

*LogP

2.48(EXP)

*Water Solubility

11(EST) at 25C

External Links

• [1]Pubchem
• [2]KEGG Drug
• [3]Drugbank

Categories:Hormones