Cholecystokinin-58
From DrugPedia: A Wikipedia for Drug discovery
Contents |
Description
Cholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source Organism
Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular Localization
Secreted.
Developmental Stage
Similarity
Belongs to the gastrin/cholecystokinin family.
Post translational Modification
The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
