Nuclear receptor subfamily 2 group B member 2-B
From DrugPedia: A Wikipedia for Drug discovery
Contents |
Source Organism
Danio rerio (Zebrafish) (Brachydanio rerio).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio.
Subcellular Localization
Nucleus.
Developmental Stage
Expressed both maternally and zygotically.
Similarity
Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post translational Modification
Function
Nuclear hormone receptor. Involved in the retinoic acid response pathway. Does not bind 9-cis retinoic acid (9C-RA). Transcriptionally inactive on RXR response elements. May function to negatively modulate thyroid hormone-dependent transcription.
