Nuclear receptor subfamily 3 group B member 1;

From DrugPedia: A Wikipedia for Drug discovery

Revision as of 07:58, 13 February 2009 by Raghavagps (Talk | contribs)
Jump to: navigation, search

Contents

Source Organism

Canis familiaris (Dog).

Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.

Subcellular Localization

Nucleus (By similarity).

Developmental Stage

Similarity

Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.

Post translational Modification

Phosphorylated (Probable).

Function

Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus (By similarity).

Categories:Receptors