Beta-1 adrenergic receptor

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Source Organism 2 Taxomomy 3 Subcellular Localization 4 Developmental Stage 5 Similarity 6 Post translational Modification 7 Function

Source Organism

Xenopus laevis (African clawed frog).

Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.

Subcellular Localization

Cell membrane; multi-pass membrane protein.

Developmental Stage

Similarity

Belongs to the G-protein coupled receptor 1 family.

Post translational Modification

Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity).

Function

Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins (By similarity).

Categories:Receptors