Prostaglandin E2

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.

General Properties

*Molecular Weight

352.47

*Molecular Formula

C₂₀H₃₂O₅

*IUPAC NAME

(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid

*Canonical Smiles

CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O

*Isomeric Smiles

CCCCC[C@@H](C=C[C@H]1[C@@H](CC(=O)[C@@H]1CC=C/CCCC(=O)O)O)O

PhysioChemical Properties

*Melting Point

67(EXP)

*LogP

2.82(EXP)

*Water Solubility

58.1(EST)

External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]KEGG Drug
• [4]Human Metabolome DataBase
• [5]Drugbank

Categories:Hormones