Prostaglandin D2

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.

General Properties

*Molecular Weight

352.47

*Molecular Formula

C₂₀H₃₂O₅

*IUPAC NAME

(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid

*Canonical Smiles

CCCCCC(C=CC1C(C(CC1=O)O)CC=CCCCC(=O)O)O

*Isomeric Smiles

CCCCC[C@@H](C=C[C@@H]1[C@H]([C@H](CC1=O)O)CC=C/CCCC(=O)O)O

PhysioChemical Properties

*Melting Point

*LogP

*Water Solubility

External Links

• [1]Pubchem
• [2]]1RY0,
• [3]KEGG Compound
• [4]Human Metabolome DataBase
• [5]Drugbank

Categories:Hormones