Progestrone

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.

General Properties

*Molecular Weight

314.46

*Molecular Formula

C₂₁H₃₀O₂

*IUPAC NAME

(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C

*Isomeric Smiles

CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

PhysioChemical Properties

*Melting Point

121(EXP)

*LogP

3.87(EXP)

*Water Solubility

8.81(EXP) at 25C

External Links

• [1]Pubchem
• [2]]1W0F,[[3]]1YA3,[[4]]2AA5,[[5]]2AA6,[[6]]2ABA,[[7]]2HZQ,[[8]]2O5Y,[[9]]1DBB,[[10]]1A28,
• [11]KEGG Compound
• [12]KEGG Drug
• [13]Human Metabolome DataBase
• [14]Drugbank

Categories:Hormones