Eikenella corrodens
From DrugPedia: A Wikipedia for Drug discovery
Eikenella corrodens
It is a fastidious gram-negative facultative anaerobic bacillus. It was first identified by M. Eiken in 1958, who called it Bacteroides corrodens. E. corrodens is a pleomorphic bacillus that sometimes appears coccobacillary and typically creates a depression (or "pit") in the agar on which it is growing. It grows in aerobic and anaerobic conditions, but requires an atmosphere enhanced by 3–10% carbon dioxide. The colonies are small and greyish, they produce a greenish discoloration of the underlying agar and smell faintly of bleach (hypochlorite). Only half produce the pitting of the agar that is considered characteristic. They are oxidase-positive, catalase-negative, urease-negative, indole-negative and reduce nitrate to nitrite.
| Kingdom | Bacteria |
|---|---|
| Phylum | Proteobacteria |
| Class | Beta Proteobacteria |
| Order | Neisseriales |
| Family | Neisseriaceae |
| Genus | Eikenella |
| Species | E. corrodens |
| Binomial | Eikenella corrodens |
[edit] Surface Characteristics
The LPS of E. corrodens was found to have little 2-keto-3-deoxyocutulosonic acid (KDO) and heptose and fairly strong classical endotoxic activities.
[edit] Pathogenic Activity
E. corrodens is a commensal of the human mouth and upper respiratory tract. It is an unusual cause of infection and when it is cultured, it is most usually found mixed with other organisms. Infections most commonly occur in patients with cancers of the head and neck, but it is also common in human bite infections, especially "reverse bite" or "fight bite", or "clenched fist injuries". It also causes infections in insulin-dependent diabetics and intravenous drug users who lick their needles ("needle-licker's osteomyelitis"). It is one of the HACEK group of infections which are a cause of culture-negative endocarditis.
