PolysacDB Cell wall antigen (SA I/II) 2405

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Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Cell wall antigen (SA I/II)

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Streptococcus mutans serotype c

[edit] Basic Structure

N/A

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Cell wall antigen (SA I/II)

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab Guy 1

[edit] Antibody type and class

IgG2a

[edit] Assay System

solid-phase radioimmunoassy, Competitive inhibition experiments

[edit] Cross-reactivity

This Mab was raised against specific carbohydrate epitopes on the SA and not against contaminating c polysaccharide in the SA preparation and was specific to serotype c

[edit] Proposed epitopes

glucose is part of the epitopes of SA recognized by this Mab

[edit] Proposed Utility

his Mab can be used in local passive immunization to prevent colonization of S. mutans and the development of caries in monkeys and to prevent colonization of S. mutans in human subjects

[edit] Weblink

PubMed

[edit] External Links

• Link to PolysacDB database