PolysacDB 2348
From DrugPedia: A Wikipedia for Drug discovery
Carbohydrate Name
K antigens [Capsular polysaccharide]
Carbohydrate Class
Capsular polysaccharide
Source Microbe
Sinorhizobium meliloti strain NRG34
Basic Structure
The K antigens of Sinorhizobium spp. are major strain-specific antigens, which commonly consist of small repeating units of a hexose and 1-carboxy-2-keto-3-deoxy sugars, such as sialic acid or 3-deoxy-D-manno-2-octulosonic acid (Kdo), although they vary in glycosyl residue composition, substitution patterns, linkage points, anomeric configuration, and size range. The K-antigens of rhizobia do not possess a lipid anchor
Proposed functions
K antigens may be involved in an early recognition step in S. meliloti-alfalfa interactions and that K antigen production is affected by plant-derived signals
Antigenic Nature used to produce antibodies
Whole cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab 7
Antibody type and class
IgGM
Assay System
ELISA and immunoblotting
Cross-reactivity
This Mab was specific to S. melliloti
Proposed epitopes
N/A
Proposed Utility
The use of MAbs to study specific cell surface components from the bacteroids of Rhizobium leguminosarum have yielded interesting information about morphogenesis in the pea symbiont, including the temporal expression of specific epitopes during nodule development
