PolysacDB Vi antigen 2175

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Vi antigen

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Salmonella typhi 620Ty

[edit] Basic Structure

Vi antigen is a linear homopolymer of 1-->4(2-deoxy-2-N-acetylgalacturonic acid)

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Purified Vi antigen

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab Vi4a

[edit] Antibody type and class

IgG2b

[edit] Assay System

passive hemagglutination (PHA) and enzyme-linked immunosorbent assay (ELISA), Whole-cell radioimmunoassay, dot radioimmunoassay

[edit] Cross-reactivity

This Mab recognized the Vi antigen in Citrobacter strain 5396/38 and also reacted with the Vi antigens in S. typhi and S. dublin strains

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

The Vi-agglutiniating ability of the Mab might have application in the identification of S. typhi

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database