PolysacDB O-polysaccharide 2064

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

O-polysaccharide

Carbohydrate Class

O-polysaccharide [LPS]

Source Microbe

Pseudomonas syringae serogroup O1 strain avellanae ISPaVe C4

Basic Structure

O-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab Ps1a1

Antibody type and class

IgG1

Assay System

ELISA, agglutination and immunoblotting

Cross-reactivity

"This Mab reacted with linear chemotype 1A, mixed chemotype 1C-1A with a high content of the linear O repeat 1A but did not react with those of chemotypes 1B, 1C, and 1D"

Proposed epitopes

N/A

Proposed Utility

This Mab agglutinated heat-killed homologous bacterial cells

Weblink

PubMed Central

External Links

• Link to PolysacDB database