PolysacDB O-polysaccharide 2062

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

O-polysaccharide

Carbohydrate Class

O-polysaccharide [LPS]

Source Microbe

Pseudomonas syringae IMV P-55 pv. Morsprunorum

Basic Structure

O-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab Ps2d

Antibody type and class

IgG3

Assay System

Agglutination, Ouchterlony immunodiffusion, ELISA, SDS-PAGE, and Western immunoblotting

Cross-reactivity

MAb Ps2d reacted with some strains with pathovar morsprunorum and also reacted with GSPB 839 as well as all strains with pathovar lapsa

Proposed epitopes

The epitope of Mab 2d is related to the lateral immunodominant (α1-4)D-fucose residues

Proposed Utility

This Mab strongly agglutinated homologous bacterial cells and precipitated soluble antigens

Weblink

PubMed Central

External Links

• Link to PolysacDB database