PolysacDB Cell surface polysaccharide alginate 2052

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Contents

Carbohydrate Name

cell surface polysaccharide alginate

Carbohydrate Class

Miscellaneous

Source Microbe

Pseudomonas aeruginosa

Basic Structure

N/A


Proposed functions

N/A

Antigenic Nature used to produce antibodies

Purified alginate

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab F428

Antibody type and class

IgG1

Assay System

ELISA and protection assays

Cross-reactivity

N/A

Proposed epitopes

intact carboxylate groups on the C6 carbon of the mannuronic acid residues

Proposed Utility

This Mab was found to promote phagocytic killing of both mucoid and nonmucoid strains as well as conferred protection against both types of strains in a mouse model of acute pneumonia

Weblink

PubMed

External Links

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