PolysacDB Exopolysaccharide 2051

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Exopolysaccharide

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Burkholderia pseudomallei

[edit] Basic Structure

N/A

[edit] Proposed functions

It is a virulence determinant

[edit] Antigenic Nature used to produce antibodies

Heat inactivated whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 3015

[edit] Antibody type and class

IgG1

[edit] Assay System

ELISA, immunoblotting, immunoelectron microscopy

[edit] Cross-reactivity

This Mab cross-reacts only with Burkholderia mallei and other Burkholderia pseudomallei species

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

The isolated MAb will help to elucidate the role of antibodies against the exopolysaccharide in the defense of B. pseudomallei in experimental models

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database