PolysacDB O-polysaccharide 2019

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

O-polysaccharide

Carbohydrate Class

O-polysaccharide [LPS]

Source Microbe

Pseudomonas aeruginosa serotype 1

Basic Structure

The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-

Proposed functions

N/A

Antigenic Nature used to produce antibodies

antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 1.5

Antibody type and class

N/A

Assay System

N/A

Cross-reactivity

This Mab was specific to serotype 1 LPS

Proposed epitopes

N/A

Proposed Utility

N/A

Weblink

FEMS Microbiology Letters Vol. 27 Issue 2 Pages 247-251, 1985

External Links

• BCSDB Structural Detail

• Link to PolysacDB database