PolysacDB Capsular polysaccharide 1921

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Pneumococci spp.

[edit] Basic Structure

The capsular polysaccharide of Pneumococcus sp. 14 consists of the following residues : -4)-β-D-Glcp-(1-->6)-β-D-GlcpNAc [branched to β-D-Galp-(1-->4)] -(1-->3)-β-D-Galp-(1-

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

a vaccine preparation of type 23 pneumococcal capsular polysaccharide

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Polysera

[edit] Antibody type and class

N/A

[edit] Assay System

Hemolytic plaque assay

[edit] Cross-reactivity

The antisera cross-reacted with S14, S19, or S6 capsular polysaccharides

[edit] Proposed epitopes

The antisera was proposed to be directed against a immunodominant polysaccharide PnC

[edit] Proposed Utility

N/A

[edit] Weblink

PubMed Central

[edit] External Links

• BCSDB Structural Detail

• Link to PolysacDB database