PolysacDB Lipopolysaccharide 1906

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Pasteurella multocida serotype 12

[edit] Basic Structure

LPS molecule is composed of three regions consisting of lipid A, core oligosaccharides, and O-antigen polysaccharides

[edit] Proposed functions

LPS is well known for its biological activities, including modification of metabolic activity and phagocytic function, alteration of migration of neutrophils and macrophages, and mitogenesis of lymphocytes

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Antisera

[edit] Antibody type and class

N/A

[edit] Assay System

ELISA

[edit] Cross-reactivity

This antisera cross-reacted with serotype 4 cells

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This antisera may be useful in defining antigenic determinants of LPS.

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database