PolysacDB Glucosyl ceramide 1895

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Glucosyl ceramide

Carbohydrate Class

Miscellaneous

Source Microbe

Paracoccidiodes brasiliensis

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab MEST2

Antibody type and class

IgG2a

Assay System

High performance thin layer chromatography immunostaining, solid phase radioimmunoassay

Cross-reactivity

This Mab cross-reacts with glucosyl ceramide from Histoplasma capsulatum, Sporothrix schenckii, Aspergillus fumigatus, Candida albicans, Cryptococcus neoformans, Cryptococcus laurentii and Cryptococcus albidus

Proposed epitopes

β-D-glucose residues and 2-hydroxyl groups in the fatty acid groups seemed to a important part of the epitoipe

Proposed Utility

This Mab should act as an effective reagent in studies for the distribution of glycoinositol-phosphoryl ceramides in the plasma membrane of different fungi

Weblink

PubMed

External Links

• Link to PolysacDB database