PolysacDB Capsular polysaccharide 1861

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Neisseria meningitidis group C strain C11

Basic Structure

It consists of a homopolymer of α(2-->9)-linked sialic acid residues

Proposed functions

It is an important virulence factor

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 78.2

Antibody type and class

IgG2b

Assay System

Fluorescence ELISA, Ouchterlony precipitation, Bacterial agglutination assay, Bactericidal assay

Cross-reactivity

This Mab was highly specific to group C polysaccharide and did not react with K1 polysaccharide

Proposed epitopes

N/A

Proposed Utility

This Mab had bactericidal activity

Weblink

PubMed

External Links

• Link to PolysacDB database