PolysacDB Lipopolysaccharide 1784

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Myxococcus xanthus

Basic Structure

It consists of Lipid A region covalently linked to the core region

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 1733

Antibody type and class

IgG

Assay System

ELISA, immunoblotting

Cross-reactivity

This Mab was specific to M. xanthus and did not bind to LPS of any other gram negative bacteria

Proposed epitopes

O-antigen of the LPS seems to constitute the epitope

Proposed Utility

This MAb may be a useful probe for detecting specific alterations in the LPS structure which may occur during the development of M. xanthus. This Mab has been used to isolate many LPS biosynthesis mutants

Weblink

PubMed Central

External Links

• BCSDB Structural Detail

• Link to PolysacDB database