PolysacDB Lipopolysaccharide 1561

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Leptospira interrogans serovar copenhageni

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

a suspension of serovar copenhageni strain H45 leptospires

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab MUM/F 1 - 1 /copenhageni

Antibody type and class

IgA

Assay System

enzyme immunoassay, immunodiffusion and immunoblotting, Passive protection experiments

Cross-reactivity

This Mab reacted with 1 1 of the 17 serovars of the Icterohaemorrhagiae serogroup, but did not react significantly with representative serovars of the other serogroups of L. interrogans or other species of Leptospira

Proposed epitopes

N/A

Proposed Utility

This Mab opsonised viable leptospires for phagocytosis and was further shown to protect against lethal infection in susceptible animals

Weblink

PubMed

External Links

• Link to PolysacDB database