PolysacDB Unknown carbohydrate 1543

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Unknown carbohydrate

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Leishmania tropica (LRC-L137)

[edit] Basic Structure

N/A

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

L. tropica (LRC-L137) promastigotes

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab L-5-41

[edit] Antibody type and class

IgG2b

[edit] Assay System

solid-phase radioimmunoassay, Indirect fluorescent antibody test

[edit] Cross-reactivity

This Mab cross-reacted with 4 strains of L. tropica - L137, L287, L251, L38. It did not cross-react with any other Leishmania species

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab abolished capacity of the pathogen to multiply within macrophages in vitro and indeed promoted parasite killing

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database