PolysacDB Unknown carbohydrate 1543

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Unknown carbohydrate

Carbohydrate Class

Miscellaneous

Source Microbe

Leishmania tropica (LRC-L137)

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

L. tropica (LRC-L137) promastigotes

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab L-5-41

Antibody type and class

IgG2b

Assay System

solid-phase radioimmunoassay, Indirect fluorescent antibody test

Cross-reactivity

This Mab cross-reacted with 4 strains of L. tropica - L137, L287, L251, L38. It did not cross-react with any other Leishmania species

Proposed epitopes

N/A

Proposed Utility

This Mab abolished capacity of the pathogen to multiply within macrophages in vitro and indeed promoted parasite killing

Weblink

PubMed Central

External Links

• Link to PolysacDB database