PolysacDB Lipopolysaccharide 1513

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Klebsiella strains KD2

Basic Structure

O-1 side chain of the LPS is proposed to contain a disaccharide repeat unit consisting of [-α-D-Galp-(1->3)-β-D-Galf-] (1->4), where Gal is galactose

Proposed functions

These major cell surface antigens play important roles in the ability of the bacterium to evade host cell defenses

Antigenic Nature used to produce antibodies

formalinized whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Polysera

Antibody type and class

N/A

Assay System

ELISA and immunoblotting

Cross-reactivity

The antisera reacted most strongly against the HMW-LPS fraction of Kliebsiella strain KD2 but also recognized the LMW-LPS of KLebsiella strains KD37 and KD2

Proposed epitopes

N/A

Proposed Utility

This antibody may help in the stuctural and functional elucidation of O1 side chain of Klebsiella LPS

Weblink

PubMed Central

External Links

• Link to PolysacDB database