PolysacDB Lipopolysaccharide 1510

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Actinobacillus pleuropneumoniae serotype b strains 81-750 and B78-3760

Basic Structure

Consists of a polysaccharide structure of a linear unbranched

Proposed functions

LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus

Antigenic Nature used to produce antibodies

formaldehyde killed cells of strains 81-750 and B78-3760 and LPS coated whole cells of strain 81-750.

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 3B4

Antibody type and class

IgG1

Assay System

ELISA and dot ELISA

Cross-reactivity

This antibody cross-reacted strongly with CPS of serotype 5b

Proposed epitopes

N/A

Proposed Utility

This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals

Weblink

PubMed Central

External Links

• Link to PolysacDB database