PolysacDB Lipopolysaccharide 1474

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Helicobacter pylori

Basic Structure

The structure of the O-polysaccharide part of the LPS is the same as the Lewis X (Lex) and Lewis Y (Ley) determinants of the human cell surface glycoconjugates

Proposed functions

The O-polysaccharide regions of these LPS were found to be a major antigenic determinant

Antigenic Nature used to produce antibodies

N/A

Carrier Name

N/A

Conjugation Method

N/A

Antibodies

Mab H18A

Antibody type and class

IgG3

Assay System

Immunoblotting and ELISA

Cross-reactivity

This anti-Lex Mab reacted with strains CG4 and CA2, CG9 and GU10 and did not react with strains 43504-r and CG7

Proposed epitopes

N/A

Proposed Utility

N/A

Weblink

PubMed Central

External Links

• BCSDB Structural Detail

• IEDB Epitopic Detail

• Link to PolysacDB database