PolysacDB Lipopolysaccharide 1471

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Helicobacter pylori

[edit] Basic Structure

The structure of the O-polysaccharide part of the LPS is the same as the Lewis X (Lex) and Lewis Y (Ley) determinants of the human cell surface glycoconjugates

[edit] Proposed functions

The O-polysaccharide regions of these LPS were found to be a major antigenic determinant

[edit] Antigenic Nature used to produce antibodies

naturally infected patiens

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Type A Polysera

[edit] Antibody type and class

N/A

[edit] Assay System

Immunoblotting and ELISA

[edit] Cross-reactivity

This antisera reacted with the polysaccharides of GU2, DU1 and CA1 LPS only

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This antisera may yield useful information concerning the real surface of the bacterium

[edit] Weblink

[edit] External Links

• BCSDB Structural Detail

• IEDB Epitopic Detail

• Link to PolysacDB database