PolysacDB Lipopolysaccharide 1458
From DrugPedia: A Wikipedia for Drug discovery
Carbohydrate Name
Lipopolysaccharide
Carbohydrate Class
Lipopolysaccharide
Source Microbe
Haemophilus ducreyi
Basic Structure
It consist of an oligosaccharide core ketosidically linked via a 3-deoxy-D-manno-octulosonic acid (Kdo) residue to the lipid A region. The oligosaccharide core characteristic of these bacteria has been divided into two regions: (i) an inner core, consisting of three L-glycero-D-manno-heptose (Hep) residues and one phosphorylated Kdo residue, and (ii) an outer core, with one or more heterogeneous oligosaccharide branches containing mainly galactose (Gal) and glucose (Glc) residues
Proposed functions
LPS plays an important role in the infection process
Antigenic Nature used to produce antibodies
Whole cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab MAHD6
Antibody type and class
IgM
Assay System
ELISA and immunoblotting
Cross-reactivity
This antibody was specific to H. ducreyi but with none of the other Haemophilus or Bordetella spp.
Proposed epitopes
The epitope consisted of (-DD-Hepp-1-->6-β-D-Glcp-)
Proposed Utility
This Mab would aid in the classification of H. ducreyi for epidemiological purposes
