PolysacDB Exopolysaccharide 1251

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Exopolysaccharide

Carbohydrate Class

Miscellaneous

Source Microbe

Burkholderia pseudomallei NCTC 4845

Basic Structure

N/A

Proposed functions

Polysaccharide capsule of B. pseudomallei plays a role in environmental protection, immune system evasion and attachment to epithelial cells

Antigenic Nature used to produce antibodies

Heat inactivated B. pseudomallei NCTC 4845

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 4VIIIAII

Antibody type and class

IgG2a

Assay System

ELISA and immunoblotting

Cross-reactivity

N/A

Proposed epitopes

N/A

Proposed Utility

This MAb demonstrated a significant protective effect against a challenge dose of B. Pseudomallei in mice

Weblink

PubMed

External Links

• Link to PolysacDB database