PolysacDB Lipopolysaccharide 1249

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Brucella melitensis 16M

[edit] Basic Structure

Brucella LPS-PS complexes consist of the Brucella O-chains, native hapten, and polysaccharide B

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

B.melitensis 16M whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab M

[edit] Antibody type and class

N/A

[edit] Assay System

Immunoblotting, ELISA, immunoaffinity chromatography, immunoprecipitation,

[edit] Cross-reactivity

This antibody was specific to Brucella melitiensis 16M strain and did not cross-react with Brucella abortus 2308, Brucella abortus 19 and Brucella abortus type 4 strains

[edit] Proposed epitopes

This mab was specific to the M epitope

[edit] Proposed Utility

This Mab would provide a tool to monitor the expression of LPS epitopes by Brucella spp. and determine the content of preparations intended for use in the control of brucellosis

[edit] Weblink

PubMed Central

[edit] External Links

• IEDB Epitopic Detail

• Link to PolysacDB database