PolysacDB O-polysaccharide 1242
From DrugPedia: A Wikipedia for Drug discovery
Carbohydrate Name
O-polysaccharide
Carbohydrate Class
O-polysaccharide [LPS]
Source Microbe
Brucella abortus W99
Basic Structure
O-polysaccharide consists of an unbranched linear homopolymer of 10 to 100 α-1,2-linked 4-formamido-4,6-dideoxy-D-mannose (N formylperosamine) residues. The O-polysaccharide is covalently linked to a core oligosaccharide
Proposed functions
N/A
Antigenic Nature used to produce antibodies
Whole B. abortus W99 cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab 2C8C4
Antibody type and class
IgG3
Assay System
ELISA
Cross-reactivity
This Mab was specific to A strains of Brucella and did not cross-react with Brucella M strain, Y enterocolitica O:9, S-LPSs of S.urbana, Vibrio cholerae and E. coli O:157
Proposed epitopes
The epitope was proposed to be a pentasaccharide or larger oligosaccharide composed of α1,2-linked D-Rha4NFo and also contained α1,3 linkages
Proposed Utility
This Mab helped in the epitope strucure elucidation
