PolysacDB Lipopolysaccharide 1229

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Brucella abortus biotype 1

Basic Structure

LPS carries the A (B. abortus-type) and M (B. melitensis-type) epitopes, respectively. In addition, there is at least one common (C) epitope restricted to the smooth brucellae and a second common epitope (C/Y) shared with Yersinia enterocolitica O:9

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Goat polysera

Antibody type and class

N/A

Assay System

Inihibitory ELISA

Cross-reactivity

This antibody reacted with both crude LPS and the native hapten component of Brucella

Proposed epitopes

The epitope was proposed to consist of A and C epitopes

Proposed Utility

This antisera can be used for the diagnosis of brucellosis in small ruminants and cattle

Weblink

PubMed Central

External Links

• IEDB Epitopic Detail

• Link to PolysacDB database