PolysacDB Lipopolysaccharide 1182

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Bordetella pertusis 18530

[edit] Basic Structure

N/A

[edit] Proposed functions

The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties

[edit] Antigenic Nature used to produce antibodies

B. pertussis 18530 LPS

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 9-1-H5

[edit] Antibody type and class

IgM

[edit] Assay System

ELISA

[edit] Cross-reactivity

did not react with LPS prepared from B. parapertussis and B. bronchiseptica. No cross-reactions were observed with strains of Branhamella catarrhalis, Neisseria meningitidis, Streptococcus miteor, Haemophilus influenza, or Legionella pneumophila

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

N/A

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database