PolysacDB Polysaccharide B 1154

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Polysaccharide B

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Bacteroides fragilis NCTC 9344

[edit] Basic Structure

It contained fucose (15%), galactose (23%), quinovosamine (27%), and glucosamine (23%)

[edit] Proposed functions

This forms a part of the capsular polysaccharide of B. fragilis which is an important virulence factor

[edit] Antigenic Nature used to produce antibodies

formalin-killed whole B. fragilis cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab F10

[edit] Antibody type and class

IgG2a

[edit] Assay System

Immunoblotting, immunofluorescence

[edit] Cross-reactivity

N/A

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab may help in the elucidation of variability of surface polysaccharide structures

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database