PolysacDB Lipopolysaccharide 1087

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Eikenella corrodens FDC 1073

[edit] Basic Structure

The LPS of E. corrodens was found to have little 2-keto-3-deoxyocutulosonic acid (KDO) and heptose and fairly strong classical endotoxic activities

[edit] Proposed functions

The lipopolysaccharide (LPS) of the species may play a primary role in the pathogenesis

[edit] Antigenic Nature used to produce antibodies

LPS preparations from E. corrodens FDC

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab ECF-1

[edit] Antibody type and class

IgM

[edit] Assay System

ELISA, immunodiffusion, immunoblotting

[edit] Cross-reactivity

This antibody showed cross-reactivity with LPS from F. nucleatum ATCC 25586

[edit] Proposed epitopes

This Mab recognized a core region epitope

[edit] Proposed Utility

This Mab would help in the revealing of antigenic natureof the surface of Eikenella corrodens

[edit] Weblink

[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC313151 &tool=pmcentrez&rendertype=abstract PubMed Central]

[edit] External Links

• Link to PolysacDB database