PolysacDB Lipopolysaccharide 1087

From DrugPedia: A Wikipedia for Drug discovery

Revision as of 06:03, 8 April 2010 by Raghavagps (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search


Contents

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Eikenella corrodens FDC 1073

Basic Structure

The LPS of E. corrodens was found to have little 2-keto-3-deoxyocutulosonic acid (KDO) and heptose and fairly strong classical endotoxic activities


Proposed functions

The lipopolysaccharide (LPS) of the species may play a primary role in the pathogenesis

Antigenic Nature used to produce antibodies

LPS preparations from E. corrodens FDC

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab ECF-1

Antibody type and class

IgM

Assay System

ELISA, immunodiffusion, immunoblotting

Cross-reactivity

This antibody showed cross-reactivity with LPS from F. nucleatum ATCC 25586

Proposed epitopes

This Mab recognized a core region epitope

Proposed Utility

This Mab would help in the revealing of antigenic natureof the surface of Eikenella corrodens

Weblink

[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC313151 &tool=pmcentrez&rendertype=abstract PubMed Central]

External Links