Salmonella typhimurium
From DrugPedia: A Wikipedia for Drug discovery
Salmonella typhimurium
A rod-shaped Gram-negative enterobacteria; cause typhoid fever and food poisoning; can be used as a bioweapon.
| Kingdom | Bacteria |
|---|---|
| Class | Gamma Proteobacteria |
| Order | Enterobacteriales |
| Family | Enterobacteriaceae |
| Genus | Salmonella |
| Species | S. typhimurium |
| Binomial | Salmonella typhimurium |
Contents |
Surface Characteristics
LPS is composed of three parts: (1) lipid A, (2) core polysaccharide, and (3) O antigen. The lipid A region contains two glucosamine sugar derivatives, each with three fatty acids and phosphate or pyrophosphate attached. The core polysaccharide has KDO and attached to lipid A. The side chain O is small polysaccharide chain extending outward from the core, it has several peculiar sugars and varies in composition between bacterial strains.
Transmission
Salmonella infections are zoonotic and can be transferred between humans and nonhuman animals. Many infections are due to ingestion of contaminated food.
Pathogenic Activity
S. Typhimurium, causes a wide range of infections in birds and mammals, ranging from self-limiting gastroenteritis to severe systemic paratyphoid diseases; conveyed by contaminated foodstuffs; causes Salmonella enteritis (food poisoning) in humans.
