CarboDB Core oligosaccharide 2507

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Core oligosaccharide

[edit] Carbohydrate Class

Core oligosaccharide [LPS]

[edit] Source Microbe

Vibrio cholerae 01 serogroup

[edit] Basic Structure

N/A

[edit] Proposed functions

V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera

[edit] Antigenic Nature used to produce antibodies

Purified LPS

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab E8

[edit] Antibody type and class

IgG1

[edit] Assay System

enzyme-linked immunosorbent assayinhibition experiments, Coagglutination experiments

[edit] Cross-reactivity

This Mab cross-reacted with both 0-group 1 vibrios and some non-O-group 1 vibrios

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab may provide improved opportunities for the characterization of antigenic determinants

[edit] Weblink

PubMed Central

[edit] External Links

• Link to CarboDB database