CarboDB Core oligosaccharide 2507

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Core oligosaccharide

Carbohydrate Class

Core oligosaccharide [LPS]

Source Microbe

Vibrio cholerae 01 serogroup

Basic Structure

N/A

Proposed functions

V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera

Antigenic Nature used to produce antibodies

Purified LPS

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab E8

Antibody type and class

IgG1

Assay System

enzyme-linked immunosorbent assayinhibition experiments, Coagglutination experiments

Cross-reactivity

This Mab cross-reacted with both 0-group 1 vibrios and some non-O-group 1 vibrios

Proposed epitopes

N/A

Proposed Utility

This Mab may provide improved opportunities for the characterization of antigenic determinants

Weblink

PubMed Central

External Links

• Link to CarboDB database